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Corticosteroid used to treat inflammation of the eye. Before the needed effect is achieved. Prednisone is the most commonly-prescribed oral corticosteroid. In high doses, Prednisolone also decreases the numbers of white blood cells. Prednisolone prevents the release of substances in the body that cause inflammation. Prednisone may interact with estrogens and phenytoin. Prednisone is the most commonly-prescribed oral corticosteroid. Since prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system.